Marta Peña Domingo on Muck Rack

Marta Peña Domingo

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Articles

Use of mesenchymal stromal cells derived from the Wharton’s jelly of human umbilical cord for treating patients with steroid-resistant graft versus host disease: predicting clinical response by a validated immunopotency assay

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By Silvia Torrents, Margarita Codinach, Luciano Rodríguez, Cristina Díaz de Heredia, Iván López Torija, Alberto Mussetti, Félix López Cadenas, Sergi Querol, Joaquim Vives, Ana García-Buendía, Júlia Marsal Ricomà, Marta Peña Domingo, Nerea Castillo-Flores
| Nature Verified
Abstract Steroid-resistant (SR) graft-versus-host disease (GvHD) remains a severe complication following allogeneic hematopoietic progenitor cell transplantation (HPCT). Mesenchymal stromal cell (MSC)-based therapies hold promise but face challenges in demonstrating clinical efficacy. This study investigates how in vitro immunopotency, a critical quality attribute (CQA) of MSC, correlates with patient outcomes to inform MSC-based therapy development for SR-GvHD.
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