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CONFLICT OF INTEREST STATEMENT The authors have no conflicts of interest to disclose. DATA AVAILABILITY STATEMENT Data are available upon request. Supporting Information Filename Description bjh70865-sup-0001-FigureS1.pdfPDF document, 10.8 KB Figure S1. Comparative analysis of KMT2A-PTD detection. OGM: Optical genome mapping. bjh70865-sup-0002-Supinfo.docxWord 2007 document , 15.2 KB Data S1. Supporting Information. REFERENCES 1, , , , , , et al.
This study included 431 patients diagnosed with AML based on standard WHO criteria 2017 [22], from 2017 to 2020, at the Hospital de la Santa Creu I Sant Pau in Barcelona. Patients referred to flow cytometry and molecular analysis were included in this series. In an additional series, 60 adult AML diagnosed from the Hospital de la Santa Creu I Sant Pau were enrolled in the study to perform RNA analysis and gene expression by RT-PCR.
Abstract The treatment of acute myeloid leukemia (AML) is adjusted according to cytogenetic risk factors and molecular markers. Cytarabine remains the main drug to treat AML, and several studies have explored the prognostic relevance of the genotype of cytarabine metabolizing enzymes in AML.
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