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Abstract The transforming growth factor-β (TGF-β) pathway typically inhibits tumorigenesis but can promote metastasis during cancer progression. Activin receptor-like kinase 4 (ALK4), a type I TGF-β family receptor, is frequently downregulated or mutated in cancers, and reduced ALK4 expression correlates with poorer outcomes. However, its role and mechanism of action in cancer progression remains unclear.
Whether singing the classics with friends in choir, exploring the ice age at a museum or feeling my breath catch as I view some of the world’s most famous paintings, I have been blessed by the arts my whole life. They have brought me new friendships, encouraged me to explore different cultures, dared me to dream, picked me up when I was down and taken me to places around the world — both physically and in my mind.
As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.