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Endogenous Estrogen Exposure and All-Cause Mortality Among Women with Overweight or Obesity According to Metabolic Health Status: Insights from an 18-Year Prospective Cohort Study
Introduction Estrogen exerts a broad range of physiological effects that extend well beyond the reproductive system, influencing multiple organ systems and contributing to the regulation and pathophysiology of various conditions, including metabolic disorders, obesity, type 2 diabetes mellitus (T2DM), cardiovascular disease (CVD), musculoskeletal disorders, hepatic dysfunction, and neurodegenerative diseases.1 Notably, estrogen demonstrates both protective and deleterious effects, as...
Association of childhood metabolic syndrome and metabolic phenotypes with the carotid intima-media thickness (CIMT) in early adulthood: Tehran lipid and glucose study
Highlights • Overall, the clinical significance of adolescent metabolic syndrome (MetS) in identifying future adverse outcomes is a matter of debate due to several reasons. First, identification of individuals with MetS is relatively more difficult in adolescents than adults due to indefinite recommendations for the diagnosis of MetS in this age group. Second, previous studies have suggested a marked instability in the diagnosis of MetS among adolescents.
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