Masahiko S. Satoh on Muck Rack

Masahiko S. Satoh

As seen in: Environmental Health Perspectives, MDPI
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Articles

Improvement of Spontaneous Locomotor Activity in a Murine Model of Duchenne Muscular Dystrophy by N-Acetylglucosamine Alone and in Combination with Prednisolone

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By Masahiko S. Satoh, Guillaume St-Pierre, Ann Rancourt, Maude Fillion
| biorxiv.org
Abstract N-acetylglucosamine (GlcNAc) is an endogenous compound whose intracellular concentration is closely associated with the biosynthesis of acetyllactosamine-rich N-linked oligosaccharides. These oligosaccharides interact with mammalian lectin galectin-3, mediating cell surface receptor dynamics as well as cell-to-cell and cell-to-extracellular matrix interactions. Our previous and recent studies suggest that GlcNAc, in conjunction with galectin-3, augments muscle regeneration in vitro.
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N-Acetylglucosamine Facilitates Coordinated Myoblast Flow, Forming the Foundation for Efficient Myogenesis

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By Masahiko S. Satoh, Ann Rancort, Guillaume St-Pierre, Elizabeth Bouchard
| biorxiv.org
Abstract Skeletal muscle comprises 30-40% of a mammal body mass, maintaining its integrity through efficient muscle fiber regeneration, which involves myoblast differentiation into myotubes. Previously, we reported that N-acetylglucosamine (GlcNAc) promotes myogenesis in C2C12 cells, although the underlying mechanisms were unclear.
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Cell Fate Simulation Reveals Cancer Cell Features in the Tumor Microenvironment

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By Sachiko Sato, Ann Rancourt, Masahiko S. Satoh
| biorxiv.org
Abstract To elucidate the dynamic evolution of cancer cell characteristics within the tumor microenvironment (TME), we developed an integrative method combining single-cell tracking, cell fate simulation, and three-dimensional (3D) TME modeling.
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