Mason Posner on Muck Rack

Mason Posner

Ohio
As seen in: BioRxiv
Biology prof, former dept chair, fish guy, developmental biologist and vision researcher
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Articles

Loss of αBa-crystallin, but not αA-crystallin, increases age-related cataract in the zebrafish lens

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By Taylor Kaye, Mason Posner, Taylor Garver, Stuart Brdicka
| BioRxiv
Abstract The vertebrate eye lens is an unusual organ in that most of its cells lack nuclei and the ability to replace aging protein. The small heat shock protein α-crystallins evolved to become key components of this lens, possibly because of their ability to prevent aggregation of aging protein that would otherwise lead to lens opacity. Most vertebrates express two α-crystallins, αA- and αB-crystallin, and mutations in each are linked to human cataract.
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