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Mathias Schäfersküpper on Muck Rack

Mathias Schäfersküpper

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Articles

Outcomes of allogeneic transplantation in blast-phase myeloproliferative neoplasms: one-third achieve long-term survival

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By Kordelia Barbullushi, Nico Gagelmann, Kristin Rathje, Anita Badbaran, Johanna Richter, Mathias Schäfersküpper, Franziska E. Marquard, Radwan Massoud, Evgeny Klyuchnikov, Normann Steiner, Ina Rudolph, Silke Heidenreich, Christian Niederwieser, Catherina Lück, Dietlinde Janson, Christine Wolschke, Francis Ayuk, Nicolaus Kröger, Mirjam Reichard
| Nature Verified
Abstract Philadelphia-negative myeloproliferative neoplasms (MPNs) can progress to blast phase (MPN-BP), a biologically distinct and highly lethal entity with a median survival typically under six months. Allogeneic hematopoietic stem cell transplantation (allo-HSCT) remains the only potentially curative approach, yet relapse and non-relapse mortality limit durable benefit. We retrospectively analyzed post-transplant outcomes in 51 consecutive adults undergoing 53 allo-HSCTs for MPN-BP.
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