Matías Tomás Angerami on Muck Rack

Matías Tomás Angerami

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Articles

Determination of dehydroepiandrosterone and its biologically active oxygenated metabolites in human plasma evinces a hormonal imbalance during HIV-TB coinfection

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By Maria Belen Vecchione, Guadalupe Suarez, Javier Eiras, Matías Tomás Angerami
| Nature Verified
In the current study, we propose a novel HPLC-MS/MS-based approach to simultaneously measure DHEA, AED, AET and 7-oxo-DHEA in human plasma. HPLC–MS/MS has been used in clinical laboratories during the last 10–15 years, and steroids were among the first molecules to be quantified using this technology38. Triple quadrupole mass spectrometry has emerged as a tool for improving detection sensitivity and resolution, which results in a simultaneous qualitative and quantitative measurement.
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