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Purinergic signaling via P2X receptors and mechanisms of unregulated ATP release in the outer retina and age-related macular degeneration
Haydn Molcak1, Kailun Jiang1, Christopher J. Campbell2 and Joanne A. Matsubara1* 1Matsubara Lab, Faculty of Medicine, Department of Ophthalmology and Visual Sciences, Eye Care Centre, Vancouver, BC, Canada 2Paragon Ventures Inc, Vancouver, BC, Canada Age-related macular degeneration (AMD) is a chronic and progressive inflammatory disease of the retina characterized by photoceptor loss and significant central visual impairment due to either choroidal neovascularization or geographic atrophy.
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