Matthan W.A. Caan on Muck Rack

Matthan W.A. Caan

As seen in: Nature
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Articles

On the value of radiomics in addition to clinical measures in emotional conflict fMRI for predicting sertraline response in major depressive disorder

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By Mingshi Chen, Henk A. Marquering, Henricus G. Ruhé, Liesbeth Reneman, Matthan W.A. Caan
| Nature Verified
Abstract Most patients with major depressive disorder (MDD) do not respond to first-line treatment, and robust predictors of individual outcomes are lacking. Functional MRI (fMRI) has shown promise for identifying treatment-relevant brain markers, but standard analyses often rely on mean activation within regions of interest (ROIs).
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