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Matthew Barbisan on Muck Rack

Matthew Barbisan

As seen in: Nature, Taylor & Francis Online
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Articles

Drug repurposing for glucosyltransferase inhibition for targeted oral biofilm disruption

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By Matthew Logan, Steven Lewis, Hua Zhang, Matthew Barbisan, Marcelo Y. Icimoto, Hui Wu, Dustin Higashi, Justin Merritt, Jonathon Baker, Carmem Pfeifer, Fernanda S. de Lucena
| Nature Verified
Abstract Microbial dysbiosis is the root cause for many diseases. The acidogenic Streptococcus mutans (S.m.) forms a exopolysaccharide-rich biofilm (EPS), mediated by species-specific glucosyltransferases (Gtf), which synthesizes both soluble and insoluble glucans directly on the bacterial surface. GtfC was selected as the primary druggable target since its activity is essential for biofilm initiation and cohesion.
Open in Who Shared Issue with article?

The effect of Beta vulgaris on an in vitro oral microbiome of electronic cigarette users

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By Jonah Tang, Justin Nussbaum, Daniela V. Staton, Matthew Barbisan
| Taylor & Francis Online
ABSTRACT Background Although touted as a safer alternative to cigarette smoking, electronic cigarette usage has been increasingly linked to a myriad of health issues and appears to impact the oral microbiome. Meanwhile, nitrate supplementation has shown promise as a prebiotic that induces positive effects on the oral microbiome.
Open in Who Shared Issue with article?
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