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Articles by Matthew Budde
Cervical spinal cord angiography and vessel‐selective perfusion imaging in the rat
CONFLICT OF INTEREST STATEMENT The authors declare no potential sources of conflict of interest. REFERENCES 1, , . Arterial spin labeling for the measurement of cerebral perfusion and angiography. J Cereb Blood Flow Metab. 2018; 38(4): 603-626. doi:10.1177/0271678X17743240 2, , , et al. Recommended implementation of arterial spin-labeled perfusion MRI for clinical applications: A consensus of the ISMRM perfusion study group and the European consortium for ASL in dementia. Magn Reson Med.
Microstructural Tissue Changes in a Rat Model of Mild Traumatic Brain Injury
Introduction Magnetic resonance imaging (MRI) and computed tomography (CT) are routinely used to assess tissue damage in patients after traumatic brain injury (TBI; Duhaime et al., 2010). While these imaging methodologies can assess tissue damage after moderate and severe injury, mild TBI (mTBI) remains a challenge by not providing clear radiological evidence of brain injury (Mittl et al., 1994; Iverson et al., 2000; Scheid et al., 2003; Hughes et al., 2004).
Diffusion tensor distribution imaging of an in vivo mouse brain at ultrahigh magnetic field by spatiotemporal encoding
Abstract Diffusion tensor distribution (DTD) imaging builds on principles from diffusion, solid‐state and low‐field NMR spectroscopies, to quantify the contents of heterogeneous voxels as nonparametric distributions, with tensor “size”, “shape” and orientation having direct relations to corresponding microstructural properties of biological tissues.
Diffusion tensor distribution imaging of an in vivo mouse brain at ultrahigh magnetic field by spatiotemporal encoding
Abstract Diffusion tensor distribution (DTD) imaging builds on principles from diffusion, solid‐state and low‐field NMR spectroscopies, to quantify the contents of heterogeneous voxels as nonparametric distributions, with tensor “size”, “shape” and orientation having direct relations to corresponding microstructural properties of biological tissues.
Axonal injury detected by in vivo diffusion tensor imaging correlates with neurological disability in a mouse model of multiple sclerosis
Recent studies have suggested that axonal damage, and not demyelination, is the primary cause of long‐term neurological impairment in multiple sclerosis and its animal model, experimental autoimmune encephalomyelitis (EAE). The axial and radial diffusivities derived from diffusion tensor imaging have shown promise as non‐invasive surrogate markers of axonal damage and demyelination, respectively.
Reduction of Diffusion-Weighted Imaging Contrast of Acute Ischemic Stroke at Short Diffusion Times
Background and Purpose—Diffusion-weighted imaging (DWI) of tissue water is a sensitive and specific indicator of acute brain ischemia, where reductions of the diffusion of tissue water are observed acutely in the stroke lesion core. Although these diffusion changes have been long attributed to cell swelling, the precise nature of the biophysical mechanisms remains uncertain.
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