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Matthew Mitchell

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Articles

Recurrent structural variation and recent turnover at the 17q21.31 locus in humans and great apes

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By Samvardhini Sridharan, Runyang Nicolas Lou, Scott Ferguson, Joana Rocha, Rishi De-Kayne, Matthew Mitchell, Brenna M. Henn, Peter H. Sudmant, Alison N. Killilia
| Nature Verified
Abstract The 17q21.31 locus in humans harbors several complex structural haplotypes including a ~ 970 kb inversion. Different inversion haplotypes have been associated with susceptibility to microdeletions causing Koolen-de Vries syndrome and variation in fecundity and recombination rates. Here, using 210 haplotype-resolved human genome assemblies and pangenome graph-based approaches we characterize 11 distinct structural haplotypes, several of which have not been previously described.
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Commentary: Fueled by federalism, America’s economically freest states come out on top

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By Matthew Mitchell
| Daily Republic Verified
Do economic rivalries between Texas and California or New York and Florida feel like yet another sign that America has become hopelessly divided? There is a bright side to their disagreements, and a new ranking of economic freedom across the states helps explain why. As a popular bumper sticker among economists proclaims: “I heart federalism (for the natural experiments).” In a federal system, states have wide latitude to set priorities and to choose their own strategies to achieve them.
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By Matthew Mitchell
| Walla Walla Union-Bulletin Verified
Do economic rivalries between Texas and California or New York and Florida feel like yet another sign that America has become hopelessly divided? There is a bright side to their disagreements, and a new ranking of economic freedom across the states helps explain why. As a popular bumper sticker among economists proclaims: “I heart federalism (for the natural experiments).” In a federal system, states have wide latitude to set priorities and to choose their own strategies to achieve them.
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