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Matthias Baudot on Muck Rack

Matthias Baudot

As seen in: BioRxiv
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Articles

Aging reduces the number and function of L-type calcium channels in the membrane of cardiac pacemaker cells

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By Oscar Vivas, Sabrina Choi, Víctor Flores Verified, Matthias Baudot
| BioRxiv
Abstract Every heartbeat is initiated by a spontaneous electrical signal generated inside the cardiac pacemaker. The generation of this electrical signal depends on the coordinated opening and closing of different ion channels, where voltage-gated L-type calcium channels play a central role. Despite the reliability of the pacemaker, all mammals experience a linear slowdown of the pacemaker rate with age.
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