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Cognitive Function, Sleep, and Neuroinflammatory Markers in Mice Exposed to Very Long-Term Intermittent Hypoxia
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Recovery Mimicking “Ideal” CPAP Adherence Does Not Improve Wakefulness or Cognition in Chronic Murine Models of OSA: Effect of Wake-Promoting Agents
Mohammad Badran [1] ; Clementine Puech [1] ; Max B. Barrow [2] ; Alexandra R.
IJMS | Free Full-Text | Cognitive Impairments, Neuroinflammation and Blood-Brain Barrier Permeability in Mice Exposed to Chronic Sleep Fragmentation during the Daylight Period
4. Materials and Methods All experiments were approved by the Institutional Animal Care and Use Committee (IACUC) of the University of Missouri (IACUC 9720). All efforts were made to minimize animal suffering and to reduce the number of animals. Seventy male C57BL/6 J mice (8-week-old) were purchased from Jackson Laboratory (Bar Harbor, ME, USA).
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