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Maximiliane Montag

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Articles

Modeling Bioavailable Concentrations in Zebrafish Cell Lines and Embryos Increases the Correlation of Toxicity Potencies across Test Systems

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By Sebastian Lungu-Mitea, Carolina Vogs, Gunnar Carlsson, Maximiliane Montag
| ACS Publications
Introduction Toxicological risk assessment and regulatory decision making, such as the REACH directive,(1) TSCA reauthorization,(2) and others,(3−6) have collaterally increased animal testing,(7,8) a development contradictory to efforts made to reduce, replace, and refine (“3Rs”)(9) the usage of animals for both human toxicology(10−12) and ecotoxicology.(13,14) Given that we live in an ever-growing chemical environment, the plethora of xenobiotic compounds surrounding us needs to be assessed...
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