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Mayra Delgado-Ramírez on Muck Rack

Mayra Delgado-Ramírez

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Articles

Regulation of Kv2.1 channel inactivation by phosphatidylinositol 4,5-bisphosphate

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By Mayra Delgado-Ramírez, Iván A. Aréchiga-Figueroa, Jorge Arreola, Scott K. Adney
| Nature Verified
Patch excision leads to a gradual loss of PIP from the plasma membrane, and alterations of channel function that accompany patch excision can reflect PIP dependence. For instance, rundown and changes in the voltage-dependence of Kv1.2 channels in inside-out patches can be reduced by manipulations that slow the loss of PIP and can be reversed by application of exogenous PIP to the intracellular face of the patch11.
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