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Meagn Hamblin

As seen in: BioRxiv
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Salmonella enterica serovar Typhi uses two type 3 secretion systems to replicate in human macrophages and to colonize humanized mice

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By Ramya Narasimhan, Meagn Hamblin, Ruth Schade
| BioRxiv
New Results doi: https://doi.org/10.1101/2023.06.06.543980 Abstract Salmonella enterica serovar Typhi (S. Typhi) is a human-restricted pathogen that replicates in macrophages. In this study, we investigated the roles of the S. Typhi Type 3 secretion systems (T3SSs) encoded on Salmonella Pathogenicity Islands (SPI) -1 (T3SS-1) and -2 (T3SS-2) during human macrophage infection. We found that mutants of S.
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