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Meehan SA

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Articles

The immune ensemble behind mogamulizumab-associated rash

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By Oleg Akilov, Naidu MP, Meehan SA
| Wiley Online Library Verified
The study by Meledathu et al.1 offers a finely resolved single-cell portrait of the cutaneous immune landscape during mogamulizumab-associated rash (MAR), revealing a tissue environment that is clearly altered and newly permissive to immune activity. The most immediately visible feature is enrichment of cytotoxic T-cell programmes, a finding that naturally invites a CD8-centred interpretation of MAR as a state of immune activation and, potentially, therapeutic engagement.
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