Meghan Stringer Musselman

Existing pharmacologic options for schizophrenia have limited efficacy in treating cognitive and negative symptoms. Potassium channels are found throughout the brain and help to modulate and regulate neurotransmitter release, including dopamine and glutamate. Potassium Kv3 channels are located on parvalbumin-positive (PV+) interneurons which generate gamma oscillations and are dysregulated in schizophrenia.

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