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As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.Articles
The Effectiveness of Imipenem–Relebactam against Ceftazidime-Avibactam Resistant Variants of the KPC-2 β-Lactamase
Abstract : Background: Ceftazidime-avibactam was approved by the FDA to treat infections caused by Enterobacterales carrying blaKPC-2. However, variants of KPC-2 with amino acid substitutions at position 179 have emerged and confer resistance to ceftazidime-avibactam. Methods: The activity of imipenem-relebactam was assessed against a panel of 19 KPC-2 D179 variants. KPC-2 and the D179N and D179Y variants were purified for biochemical analyses.
Sarcopenia and obesity among patients with soft tissue sarcoma - Association with clinicopathologic characteristics, complications and oncologic outcome: A systematic review and meta-analysis - European Journal of Surgical Oncology
Abstract Background and aims Sarcopenia and obesity may be associated with negative outcomes in many cancers, but their prevalence and impact in modern regimens for soft-tissue sarcoma (STS) have not been systematically studied. This study summarises and critically evaluates the current evidence-based literature on body mass index (BMI) and body composition among patients with STS, with respect to clinical and pathologic characteristics, treatment-associated morbidity and oncologic outcome.
A Standard Numbering Scheme for Class C β-Lactamases
A Standard Numbering Scheme for Class C β-Lactamases Andrew R. Mack, Melissa D. Barnes, Magdalena A. Taracila, Andrea M. Hujer, Kristine M. Hujer, Gabriel Cabot, Michael Feldgarden, Daniel H. Haft, William Klimke, Focco van den Akker, Alejandro J. Vila, Andrea Smania, Shozeb Haider, Krisztina M. Papp-Wallace, Patricia A. Bradford, Gian Maria Rossolini, Jean-Denis Docquier, Jean-Marie Frère, Moreno Galleni, Nancy D. Hanson, Antonio Oliver, Patrick Plésiat, Laurent Poirel, Patrice Nordmann, Timothy G.
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