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Melissa Rosenthal on Muck Rack

Melissa Rosenthal

San Diego
As seen in: Medium, Nature, PLOS, Business Wire, Fast Company, Flipboard, Cheddar News, PR Week, eLife, Fast Company Middle East
Co-founder @Outlever/ fmr Chief Creative Officer @ClickUp / EVP @Cheddar 🧀/ VP, Global Creative @BuzzFeed / @forbes #30under30 / Investing in Crypto since '88
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Articles

The Plasmodium heme detoxification protein functions in mitochondrial protein synthesis

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By Melissa Rosenthal, Joachim Kloehn, Tanja Ziesmann, Coralie Boulet, Ute Distler, Daniel Goldberg, Joachim M. Matz, Louis Sarrazin, Yasmin Schmitz, Anna-Lena Sandtmann, Robert Domènech-Eres, Katharina Scholz-Höhn
| Nature Verified
Abstract Malaria blood-stage parasites digest ~80% of host cell hemoglobin within a degradative vacuole, releasing heme that is detoxified by sequestration into hemozoin crystals. Although essential for survival and a validated drug target, the mechanisms of heme biomineralization remain unclear. Here, we study the parasite’s Heme Detoxification Protein (HDP), previously proposed to mediate hemozoin formation, using genetic, microscopic, bioenergetic, and proteomic approaches.
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Operational research in infectious disease outbreak response: An analysis of the World Health Organization’s Disease Outbreak News

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By Melissa Rosenthal, Jeni Stolow
| PLOS
Loading metrics Open Access Peer-reviewed Research Article Citation: Rosenthal M, Stolow J, Vogt F, Barnsley H, Caine E, Garone D, et al. (2026) Operational research in infectious disease outbreak response: An analysis of the World Health Organization’s Disease Outbreak News. PLOS Glob Public Health 6(7): e0005802.
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4-Aminoquinolines block heme iron reactivity and interfere with artemisinin action

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By Melissa Rosenthal, Daniel Goldberg
| eLife
eLife Assessment This is an important study with direct implications for the rational selection of antimalarial drug combinations. The authors present data demonstrating antagonism between 4-aminoquinoline antimalarials and peroxide drugs under physiologically relevant conditions, including robust effects at the trophozoite stage and for chloroquine at the ring stage.
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