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Mengli Zi

As seen in: Nature, Wiley Online Library
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Articles

Sleeve gastrectomy induces adipose browning via suppression of Asprosin and activation of the ATF3-Nrf2/HO-1 axis

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By Shuai Zhao, Yayan Fu, Ziwei Ding, Mengli Zi, Jie Wang, Jiajie Zhou, Ruiqi Li, Wei Qing Wang, Daorong Wang
| Nature Verified
Abstract Vertical sleeve gastrectomy (VSG) produces rapid metabolic improvement in obesity and type 2 diabetes mellitus (T2DM), yet the molecular basis linking surgery to adipose remodeling remains unclear. The fasting-induced adipokine Asprosin is implicated in metabolic dysregulation, but its role in white adipose tissue (WAT) browning after VSG is unknown. Asprosin expression was assessed in human adipose tissues and longitudinally after VSG.
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Nuclear KRT19 links the NF-κB-FSCN1 signaling to gastric cancer metastasis

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By Jiajie Zhou, Mengli Zi, Zijie Xu, Yifan Cheng, Ruiqi Li, Shuai Zhao, Jie Wang, Yayan Fu, Zhen Tian, Chenkai Zhang, Yiqiang Zhou, Ben Li, Qiannan Sun, Jun Ren, Daorong Wang, Longhe Sun, Dengyang Fang
| Nature Verified
Abstract Tumor metastasis is the leading cause of cancer-related mortality, yet the contribution of keratins to this process remains incompletely understood. Here, integrated single-cell and bulk transcriptomic analyses identify keratin 19 (KRT19) within a migration-activated epithelial program as a gene of potential functional relevance.
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Clinicopathological characteristics of gastric neuroendocrine neoplasms: A comprehensive analysis

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By Yubo Ma, Jinxia Chen, Mengli Zi
| Wiley Online Library Verified
1 INTRODUCTION Neuroendocrine neoplasms (NENs) represent a rare category of neoplasms, accounting for just 0.5% of all malignant neoplasms.
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