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Mengmeng Guo

As seen in: Color Research & Application, Nature, Wiley Online Library, MDPI, Alzheimer's Research and Therapy, Science Magazine, Royal Society of Chemistry, Canadian Journal of Infectious Diseases & Medical Microbiology, American Society for Microbiology (ASM), Dialnet - Universidad de La Rioja and
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Articles

Adipocyte-derived β-hydroxybutyrate confers metabolic resilience in multiple myeloma

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By Chen Song, Peng Yang, Yu Li, Tao Xia, Rui Li, Mengmeng Guo, Wenjun Li, Chenfeng Liu, Tiantian Jia, Yansheng Wang, Xunxia Bao, Qi Wang, Yuan Yao, Qian Dai, Huan Liu, Zongwei Li
| Nature Verified
Abstract Multiple myeloma (MM) remains an incurable blood cancer. Obesity is a known risk factor, but how adipocytes promote MM progression is not fully understood. Here, we uncover a metabolic crosstalk between adipocytes and MM cells that promotes MM cell survival under glucose deprivation. We show that glucose restriction activates AMPK, disrupting HSP90-IRF4 binding and rendering IRF4 susceptible to TRIM21-mediated proteasomal degradation.
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Bubble-Assisted Dynamic Confinement Enables Programmable Solid-State Photoswitching and Heterogeneous Photoresponsive Architectures

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By Mengmeng Guo, Xuanchi Yu, Zhaoyang Zhang
| Wiley Online Library Verified
Mengmeng Guo and Xuanchi Yu contributed equally to this work. Conflicts of Interest The authors declare no conflicts of interests. Data Availability Statement The data that support the findings of this study are available from the corresponding author upon reasonable request. Supporting Information Filename Description adma74453-sup-0001-SuppMat.docx15.6 MB Supporting File: adma74453-sup-0001-SuppMat.docx.
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Multicomponent Rare-Earth Metal–Organic Gels Empowered by Electro-Optical Signal Multi-Source Regulation for Dual-Modal Detection of Propyl Gallate Click to copy article link Article link copied!

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By Lin Cai, Guangrao Chen, Mengmeng Guo
| dx.doi.org
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