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Mengying Chen

As seen in: Nature, Wiley Online Library, MDPI, Taylor & Francis Online, Science Magazine, Royal Society of Chemistry, eLife
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Articles

Structural basis of lipid-dependent allosteric gating mechanisms for PC1-PC2 ion channel

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By Mengying Chen, Zhifei Wang, Gaoxingyu Huang, Tiago Morais, Yan Wang, Moushumi Afroza Mou, Dan Jing, Fayang Zhou, Zhangsuo Liu, Qiang Su, Yong Yu, Yigong Shi, Akhilraj R. Pillai, Rongyan Fan
| Nature Verified
Abstract The polycystin complex, consisting of one polycystin-1 (PC1) and three polycystin-2 (PC2), forms a cation channel localized to the primary cilium and is critically involved in autosomal dominant polycystic kidney disease (ADPKD). This study reveals an allosteric gating mechanism of the PC1-PC2 channel modulated by specific membrane lipids.
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Analyzing and formalising land indicators of LGAF, GLII and SDGs through LADM

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By Mengying Chen, Abdullah Kara, Peter Van Oosterom, Regina Orvañanos Murguía
| Taylor & Francis Online
Abstract Over the past fifteen years, LGAF, GLII, and SDGs frameworks have jointly shaped a complementary global land governance monitoring system. However, challenges remain in data fragmentation and standardised indicator computation. This study explores how ISO 19152 LADM provides a unified technical foundation to model and monitor global land indicators.
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Long Non-Coding RNA THRIL Promotes Influenza Virus Replication by Inhibiting the Antiviral Innate Immune Response

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By Mengying Chen, Jingyun Hu, Ming Gao, Xinni Zhou
| MDPI
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
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