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Mengying Ke

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GART Functions as a Novel Methyltransferase in the RUVBL1/β‐Catenin Signaling Pathway to Promote Tumor Stemness in Colorectal Cancer

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By Chao Tang, Mengying Ke, Xichao Yu, Shanliang Sun
| Wiley Online Library Verified
GART Contributes to CRC Cell Migration in vitro and in vivo To assess the impact of GART on CRC development, transwell assays were then performed to observe cell metastasis in both WT and GART-OE HCT-116 and RKO cells. These experiments showed that GART could promote CRC cell migration (Figure 2A,B). On the other hand, reducing the level of GART expression resulted in diminished CRC cell migration (Figure 2C,D).
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