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Mereside Alderley Park

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Articles

Modelling and breaking down the biophysical barriers to drug delivery in pancreatic cancer

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By Delanyo Kpeglo, Malcolm Haddrick, Mereside Alderley Park, Alderley Edge
| Royal Society of Chemistry Verified
Modelling and breaking down the biophysical barriers to drug delivery in pancreatic cancer† The pancreatic ductal adenocarcinoma (PDAC) stroma and its inherent biophysical barriers to drug delivery are central to therapeutic resistance. This makes PDAC the most prevalent pancreatic cancer with poor prognosis. The chemotherapeutic drug gemcitabine is used against various solid tumours, including pancreatic cancer, but with only a modest effect on patient survival.
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