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Mergan Haghshenas on Muck Rack

Mergan Haghshenas

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Articles

One-pot green synthesis of a glutamine-modified calcium tartrate bio-metal-organic framework for pH-responsive delivery of palbociclib in skin cancer therapy

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By Maryam Tohidi, Banafsheh Rastegari, Mergan Haghshenas
| Nature Verified
Abstract A biocompatible nanoporous calcium tartrate (CaT)-based bio-metal–organic framework (bioMOF) was successfully synthesized via a one-pot aqueous method in the presence of glutamine (Glu) and palbociclib (PAL), acting as a structure-directing agent and therapeutic cargo, respectively. The synthesis was performed under mild alkaline conditions at room temperature using ligand: metal molar ratios of 1:1 and 2:1.
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