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Fetal fibroblast heterogeneity defines dermal architecture during human embryonic skin development

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By Fiona Watt, Meta-organism Unit
| jidonline.org
Keywords fetal fibroblasts development single-cell RNA-sequencing spatial distribution Introduction During human embryo development, organogenesis occurs from 3 post conception weeks (PCW) through 8 PCW. At 3 PCW, the process of gastrulation occurs, which establishes three distinct cell layers: the mesoderm, endoderm and ectoderm (Zhai et al., 2022 41. Zhai, J. ∙ Xiao, Z. ∙ Wang, Y. ... Human embryonic development: from peri-implantation to gastrulation Trends Cell Biol. 2022; 32:18-29 ).
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