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UNI‐494 treatment improves measures of renal dysfunction and cardiac pathology in male rats receiving L‐NAME and angiotensin II
1 INTRODUCTION Cardiovascular disease (CVD) is considered the leading cause of death worldwide. Effective CVD treatment is, in part, hampered by the complex interaction of multiple systems and signaling pathways. For example, CVD is commonly linked to chronic kidney disease (CKD) through pathways that remain unclear (Jankowski et al., 2021; Kotwal & Perkovic, 2024).
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