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Michael A. Barras on Muck Rack

Michael A. Barras

As seen in: Color Research & Application, Wiley Online Library, British Pharmacological Society, SAGE Publishing, CSIRO Publishing
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Articles

Lean body weight should guide enoxaparin dosing in obesity: A response to Roberts et al.

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By Hesham S Al-Sallami, Michael A. Barras, Daniel Wright
| British Pharmacological Society
We read with interest the recent article by Roberts et al.1 comparing various body size descriptors with anti-Xa concentrations in obese and non-obese patients treated with enoxaparin. The authors note the weight-adjusted doses of enoxaparin using actual body weight may overdose obese individuals and increase the risk of bleeding.
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Smoking, plasma concentration, antipsychotic polypharmacy and adverse drug reaction burden in clozapine outpatients

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By Nicola Warren, Michael A. Barras, Timothy Tanzer, Emilie Rutland
| SAGE Publishing
Abstract Background: Clozapine is the most effective therapy for treatment-resistant schizophrenia, yet adverse drug reactions (ADRs) limit its use. The concurrent ADR burden in outpatients and its relation to psychotropic polypharmacy, tobacco smoking and measured clozapine exposure has not been well characterised. Method: We conducted a retrospective, cross-sectional review of medical records for 360 adults receiving maintenance clozapine at a dedicated outpatient clinic.
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Incidence of aspirin resistance in high‐risk patients following elective total hip and knee arthroplasty

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By Nameer Van oosterom, Michael A. Barras, Robert Bird, Neil Cottrell
| Wiley Online Library Verified
The use of aspirin for venous thromboembolism (VTE) prophylaxis after total hip arthroplasty (THA) and total knee arthroplasty (TKA) has increased in recent years.1, 2 However, its use is controversial and international treatment guidelines have conflicting recommendations.3 Aspirin resistance (AR) in patients with cardiovascular and neurovascular diseases is reported to be 30% and linked to increased rates of thromboembolism and death.4-9 However, the incidence of AR in patients after...
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