Deborah J Luessen1, Haiguo Sun1, Molly M McGinnis1, Michael Hagstrom1, Glen Marrs2, Brian A McCool1 and Rong Chen1* 1Wake Forest School of Medicine, United States 2Wake Forest University, United States ↵* Corresponding author; email: rchen{at}wakehealth.edu Author contributions: D.J.L., B.A.M., and R.C. conceptualization; D.J.L., H.S., M.M.M., and M.H. data curation; D.J.L. software; D.J.L., H.S., and M.H. formal analysis; D.J.L., B.A.M., and R.C. funding acquisition; D.J.L. and R.C....