“Lupus belly” isn’t a diagnosis, but does describe a legitimate experience. It’s a term used for bloating, abdominal discomfort, swelling, or visible abdominal changes that may fluctuate with lupus flares or medications. Digestive symptoms are the most common symptom of “lupus belly”. Bloating, belly pressure, nausea, acid reflux, and bowel changes often occur even when other lupus symptoms are dormant or stabilized. The gut and immune system are closely connected.