Michael V. Baratta

Abstract Predicting not just if, but also when, cognitively unimpaired individuals are likely to develop onset of Alzheimerʼs disease (AD) symptoms would be useful to clinical trials and, eventually, clinical practice. Although clock models based on amyloid and tau positron emission tomography have shown promise in predicting the onset of AD symptoms, a model based on plasma biomarkers would be more accessible.

Abstract The selection of appropriate defensive behaviors in the face of potential threat is fundamental to survival. Equally important is learning to adjust and optimize defensive behaviors when there is no real danger. Despite extensive research on innate threat processing, little is known about the mechanisms by which individuals adapt their defensive behaviors in response to repeated threats that lack real danger.

The past year saw many new findings on the study of emotional regulation and processing. We have collected a few interesting findings in the area under the umbrella of “Insights in emotion regulation and processing: 2022”. The papers in the topic cover a broad range, as befits the complex array of influences that determine our ability to express and control our emotions.