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Michaela Maria Freitag

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Articles

Design Considerations for a Phase II Platform Trial in Major Depressive Disorder

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By Humboldt-Universität zu Berlin, Dario Zocholl, Elias Meyer, Michaela Maria Freitag
| Wiley Online Library Verified
1 Introduction Major depressive disorder (MDD) is a leading cause of disability worldwide, affecting an estimated 5%–6% of the population at any given time [1]. Additionally, MDD is associated with a twofold increased risk of developing other diseases and about 8–10 life years lost compared to the general population [2].
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