Michè le Sweeney on Muck Rack

Michè le Sweeney

As seen in: Physiological Reports
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Lysine deacetylase inhibition promotes relaxation of arterial tone and C‐terminal acetylation of HSPB6 (Hsp20) in vascular smooth muscle cells

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By Kelly Morrissey, Aiqing Chen, Michè le Sweeney, Achim Treumann
| Physiological Reports Verified
AbstractThere is increasing interest in establishing the roles that lysine acetylation of non nuclear proteins may exert in modulating cell function. Lysine deacetylase 8 (KDAC8), for example, has been suggested to interact with ??actin and control the differentiation of smooth muscle cells. However, a direct role of smooth muscle non nuclear protein acetylation in regulating tone is unresolved.
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