Michelle Ann Land

Abstract Genetically encoded voltage indicators have emerged as a tool for resolving neuronal spiking activity with high spatiotemporal resolution within genetically specific populations; however, their fast temporal dynamics, low signal-to-noise ratio (SNR) and fast photobleaching have posed substantial challenges limiting their broader utility and, together with suboptimal optical acquisition schemes, preventing their efficient scale-up to larger neuronal populations.

Editor’s summary Abstract Supplementary Materials References and Notes Information & Authors Metrics & Citations Check Access References Figures Tables Media Share Editor’s summary In neurons, dendrites actively contribute to neural computation, balancing cooperative interactions with the soma. However, the precise dendritic contribution to behaviorally relevant information processing remains to be elucidated. Noguchi et al.