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Michelle Wang on Muck Rack

Michelle Wang

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Articles

Electrochemical Formation of N -Nitrosodimethylamine in Nitrite-Impacted Waters Click to copy article link Article link copied!

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By Michelle Wang, Kristen A. Riedinger, Barathkumar Baskaran
| ACS Publications
Abstract Click to copy section linkSection link copied! Electrochemical water treatment is increasingly popular for a variety of applications, including resource recovery and advanced oxidation processes. In complex environmental matrices, electro-oxidative processes are known to form hazardous byproducts. This study identifies a new pathway for N-nitrosodimethylamine (NDMA) formation via nitrite electro-oxidation in spiked synthetic and natural electrolytes.
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Replicability of multivariate brain-behaviour associations depends on clinical profile

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By Michelle Wang, Brent McPherson, Bratislav Misic, Franco Pestilli, Celia M. T. Greenwood, Jean-Baptiste Poline
| Nature Verified
Abstract Recent work suggests that thousands of individuals are required in multivariate brain-behaviour analyses to obtain consistently replicable results. Some believe, however, that smaller sample sizes may be sufficient if specific subpopulations are targeted. We investigate how sample size and cohort composition influence the replicability of Canonical Correlation Analysis (CCA) results using the UK Biobank (N = 40,514).
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Clinical pharmacology insights from recent cell and gene therapy approvals relevant to pediatrics

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By Michelle Wang, Catrina M. Loucks, Facundo Garcia-Bournissen, Tamorah Lewis, Sahana Kunanayagam, Ruud H. J. Verstegen
| Nature Verified
The United States Food and Drug Administration has approved 44 cell and gene therapies as of May 2025, including 14 for pediatric use (excluding cord blood). This signifies an advancement in the treatment of diseases and conditions that, as of yet, cannot be effectively managed with available small-molecule drugs and therapeutic proteins. This review explores the pharmacokinetic and first-in-human dosing considerations unique to cell and gene therapies.
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