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Miguel Barquin on Muck Rack

Miguel Barquin

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Articles

Comprehensive repertoire of the chromosomal alteration and mutational signatures across 16 cancer types

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By Andrew Everall, Avraam Tapinos, Aliah Hawari, Alex J. Cornish, Amit Sud, Daniel Chubb Verified, Ben Kinnersley, Anna Frangou, Miguel Barquin, Josephine Misun Jung, David Church Verified, Ludmil B. Alexandrov, Richard S. Houlston, Andreas Gruber, David C. Wedge
| Nature Verified
Abstract Whole-genome sequencing (WGS) enables exploration of the full spectrum of oncogenic processes that generate characteristic patterns of mutations. Mutational signatures provide clues to tumor etiology and highlight potentially targetable pathway defects.
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