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Frailty is related to serum inflammageing markers: results from the VITAL study

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By Yannick van Sleen, Sudarshan A. Shetty, Nicolás Gutiérrez-Melo, Milou CA Venema
| biorxiv.org
Abstract Frailty describes an age-associated state in individuals with an increased vulnerability and less resilience against adverse outcomes. To score frailty, studies have employed the questionnaires, such as the SF-36 and EQ-5D-3L, or the Frailty Index, a composite score based on deficit accumulation. Furthermore, ageing of the immune system is often accompanied by a state of low-grade inflammation (inflammageing).
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