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Articles by Min Hou
Limosilactobacillus reuteri ameliorates diet-associated metabolic dysfunction in PCOS-like rats: associations with intestinal lipid remodeling and GPR120-related regulation
Abstract Background: Polycystic ovary syndrome (PCOS) is a common endocrine-metabolic disorder frequently accompanied by dyslipidemia. However, the relationships among Limosilactobacillus reuteri (L. reuteri) supplementation, gut microbiota-associated lipid remodeling, and PCOS-related metabolic dysfunction remain unclear. Methods: A high-fat diet combined with dehydroepiandrosterone-induced PCOS-like rat model (HFHA) was established to evaluate the effects of L. reuteri supplementation.
Analysis of differences in gut microbiota structure and function in Bactrian camels under different breeding patterns from northern and southern Xinjiang, China
Abstract Introduction: The lactating Xinjiang Junggar camel is a major dairy breed with excellent milk production performance. In northern Xinjiang, camels are mainly reared under traditional grazing, while those in southern Xinjiang are raised under barn feeding due to grassland scarcity. Methods: Nine lactating camels aged 6–7 years old and nine juvenile camels aged 8 months old were selected from each region.
Case Report: Prostate metastasis from pulmonary sarcomatoid carcinoma: the first reported case and clinical implications of palliative radiotherapy
Abstract Pulmonary sarcomatoid carcinoma (PSC) is a highly aggressive lung cancer subtype. Prostate metastasis is extremely rare in lung cancer, and no PSC case with immunohistochemical confirmation has been reported. We report a 68-year-old man diagnosed with left upper lobe carcinosarcoma (myogenic differentiation) on pathological biopsy. He underwent multimodal treatment, including radical resection, adjuvant chemotherapy, anlotinib targeted therapy, and local thoracic radiotherapy.
Hydrogel Chemistry in Expansion Microscopy: From Polyacrylamide to Next-Generation Swellable Polymers
Declaration on the Use of Generative AI The graphical abstract (table-of-contents figure) was created with the assistance of a generative AI image-generation tool (Nano Banana); the authors have reviewed and edited the graphic, verified its scientific accuracy, and accept full responsibility for its content.
Loss of Drosophila nucleostemin 1 disrupts ribosomal protein homeostasis and rRNA processing to trigger apoptosis via the Xrp1/Irbp18 complex
Abstract Ribosome biogenesis, a process of producing ribosomes, plays an essential role in cell survival, proliferation and apoptosis. Nucleostemin (NS) is a conserved nucleolar protein highly expressed in proliferating cells but markedly reduced in differentiated cells. Previous studies on mammalian systems have shown that loss of NS triggers p53-dependent apoptosis and impairs ribosomal RNA (rRNA) processing.
Synergistic Remodeling of Tumor Immune Microenvironment via a DNA Nanodevice Integrating STING Activation and Lysosome-Targeted PD-L1 Degradation
1 Introduction The innate immune system constitutes the first line of defense against cellular anomalies, and the cyclic GMP-AMP synthase (cGAS)-stimulator of interferon genes (STING) pathway has emerged as a cornerstone mechanism for sensing cytosolic double-stranded DNA (dsDNA), a hallmark of genomic instability, viral infection, and cellular stress [1].
Asymmetric Decarboxylative Protonation and Deuteration of Cyanoacetic Acids Using an Organometallic Proton Shuttle Click to copy article link Article link copied!
Development of Rhodium-Catalyzed Decarboxylation We used disubstituted cyanoacetic acids as the model substrate because these racemates can be readily obtained from high-volume cyanoacetates and the nitrile group retained after decarboxylation offers diverse reactivity. Nevertheless, their asymmetric decarboxylation is rarely studied compared with related compounds such as malonic and β-keto acids.
Asymmetric Decarboxylative Protonation and Deuteration of Cyanoacetic Acids Using an Organometallic Proton Shuttle Click to copy article link Article link copied!
Introduction Click to copy section linkSection link copied! As the smallest charged species in organic transformations, the transfer of proton is fast and difficult to control. Particularly, asymmetric transformations with protonation as the stereodetermining step pose great challenges for catalyst design and development. (1) Early attempts to modulate stereocontrol often employ chiral organobases with naturally occurring motifs, such as cinchona alkaloids and ephedrine derivatives (Scheme 1A).
Targeted Protein Degradation Strategies for Lung Cancers: Focusing on Epidermal Growth Factor Receptor
Ab-PROTAC antibody-PROTAC conjugates AbTAC antibody-based PROTAC ASGPR asialo-glycoprotein receptor ATP adenosine triphosphate CI-M6PR cation-independent Mannose-6-phosphate Receptor CPP cell-penetrating peptide CRBN cereblon CuAAC Cu-free strain-promoted azide-alkyne cycloaddition DC50 half-maximal degradation concentration DUB deubiquitylating enzyme E1 ubiquitin-activating enzyme E2 ubiquitin-conjugating enzyme E3 ubiquitin ligase EGFR epidermal growth factor receptor GSH glutathione HIF1α...
Multiparty Quantum Private Comparison Using Rotation Operations
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Quantum Privacy Comparison with Ry Rotation Operation
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Optimizingthe Production of High-Quality Silage from Jingkenuo 2000 Fresh Waxy Maize: The Synergistic Effects of Microbial Fertilizer and Fermentation Agents
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Quantum Private Set Intersection Scheme Based on Bell States
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Two-Party Quantum Private Comparison Protocol for Direct Secret Comparison
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Quantum Private Comparison Protocol with Cluster States
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Two-Party Quantum Private Comparison Protocol Based on Rotational Encryption
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Elevated serum pepsinogen level predicts postoperative nausea and vomiting and pain in females with obesity following laparoscopic sleeve gastrectomy - International Journal of Obesity
Abstract Postoperative nausea and vomiting (PONV) is the most common side effect after laparoscopic sleeve gastrectomy (LSG), affecting patients’ postoperative recovery and increasing the medical and economic burden. This study aimed to analyze the relationship between serum pepsinogen and PONV. Patients with obesity who underwent LSG in our center between January 2021 and December 2022 were divided into PONV and NoPONV groups and analyzed retrospectively.
Optimization Design, Mechanical Properties, and Energy Absorption Characteristics of Thin‐Walled Porous Structures Manufactured by Selective Laser Melting
Conflict of Interest The authors declare no conflict of interest. References 1 , , , , SAE Int. 2018, 3, 217. 2 , , , , , , Mater. Sci. Eng., R 2021, 144, 100606. 3 , , , , Mater. Des. 2016, 95, 518. 4 , , , , Int. J. Adv. Manuf. Technol. 2019, 104, 3489. 5 , , , , , Composites, Part B 2018, 143, 172. 6 , , , , , Composites, Part B 2017, 110, 442. 7 , , , , , , Int. J. Mech. Sci. 2023, 246, 108102. 8 , , , , Mech. Mater. 2022, 166, 104241. 9 , , , , , , , , , Mater. Des. 2020, 186, 108340. 10 , , , , , , , , Compos. Struct.
Dual Regulation of Sensitizers and Cluster Catalysts in Metal-Organic Frameworks to Boost H2 Evolution
Supporting Information As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors.
Quantum Private Comparison Based on Four-Particle Cluster State
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Efficient Quantum Private Comparison with Unitary Operations
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Catalyst-free and wavelength-tuned glycosylation based on excited-state intramolecular proton transfer - Nature Communications
Abstract The chemoselectivity of organic reactions is a fundamental topic in organic chemistry. In the long history of chemical synthesis, achieving chemoselectivity is mainly limited to thermodynamic conditions by an exogenous activation strategy. Here, we design an endogenous activation method, which can be used to control the chemoselectivity of phenol and naphthol through the photo-induced excited-state intramolecular proton transfer (ESIPT).
New Quantum Private Comparison Using Bell States
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
IVF exposure induced intergenerational effects on metabolic phenotype in mice
Abstract What is the potential transmission of metabolic phenotype from IVF offspring to the subsequent generation? An IVF mouse model was established. The F1 generation mice were produced though IVF or natural mating and the F2 generation was obtained through the mating of F1 generation males with normal females. Their metabolic phenotype, including systemic and hepatic glucolipid metabolism, was examined. It was found that IVF F1 males exhibited metabolic changes.
New Quantum Private Comparison Using Four-Particle Cluster State
1. Introduction Traditional classical cryptography primarily relies on secure encryption methods, such as symmetrical secret key encryption and asymmetrical secret key encryption, as essential components for safeguarding private information. However, secure encryption methods face severe challenges due to the development of quantum computing and the advancements of Shor’s algorithm [1] and Grover’s algorithm [2].
Comparative Analysis of Structural and Functional Properties of Dietary Fiber from Four Grape Varieties
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Organosiloxane membranes for heavy aromatic oil fractionation
Organosiloxane membranes for heavy aromatic oil fractionation The industrial separation of hydrocarbons relies on distillation. Organic solvent nanofiltration can provide an energy-efficient alternative. We prepared high performance organosiloxane membranes for fractionation of heavy aromatics. It achieved high permeance up to 0.13 L m-2 h-1 bar-1, while rejection to 88.7% of hydrocarbon contents with five aromatic rings. You have access to this article This article has not yet been cited.
Efficient Quantum Private Comparison Based on GHZ States
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Behaviors of arched tunneling segments reinforced by basalt fiber reinforced plastic rebars
In this research, basalt fiber reinforced plastic (BFRP) rebars reinforced tunneling segment (BRRTS) technique was developed. All the BFRP rebars were designed, pre-cured according to the reinforcement design and the reinforcement drawing of steel rebars reinforced concrete tunneling segments (SRRTSs).
Analysis of the Operation Mechanism of Superjunction in RC-IGBT and a Novel Snapback-Free Partial Schottky Collector Superjunction RC-IGBT
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Inducing apoptosis and ferroptosis in breast cancer therapy
Introduction Breast cancer is the most common cancer in women and one of the leading causes of cancer death worldwide.1,2 In addition to surgical intervention, chemotherapy is still considered to be the main strategy for clinically effective treatment.3,4 However, due to chemotherapy resistance and lack of treatment options, the prognosis of patients is still not ideal, so new treatment options still need to be continuously explored.
Ultra-Processed Food as Mediator of the Association between Birthweight and Childhood Body Weight Outcomes: A Retrospective Cohort Study
2. Materials and Methods 2.1. Study Design and Participants A retrospective cohort study was conducted on 3788 available children and adolescents from Shanghai, Jiaxing, Dezhou, Suqian, Taizhou and Fuyang across eastern China between 2019 and 2021. We selected cities with upper, moderate and lower levels of socioeconomic status based on data reported in 2018 by the National Bureau of Statistics of China [32] to provide a regional representative database.
Preparation of Biomass Biochar with Components of Similar Proportions and Its Methylene Blue Adsorption
Open AccessArticle by 1,2,†, 1,†, 1, 1,3, 1, 1,2, 1, 1, 1,* and 1,3,* 1 National Joint Engineering Research Center for Highly-Efficient Utilization Technology of Forestry Resources, Southwest Forestry University, Kunming 650224, China 2 Yunnan Academy of Forestry and Grassland, Kunming 650201, China 3 Lincang Academy of Forestry Sciences, Lincang 677000, China * Authors to whom correspondence should be addressed. † These authors contributed equally to this work.
Selective Proteolysis of Activated Transcriptional Factor by NIR‐Responsive Palindromic DNA Thalidomide Conjugate Inhibits the Canonical Smad Pathway
Data Availability Statement The data that support the findings of this study are available from the corresponding author upon reasonable request.
An AIE-Active NIR Fluorescent Probe with Good Water Solubility for the Detection of Aβ1-42 Aggregates in Alzheimer’s Disease
This is an early access version, the complete PDF, HTML, and XML versions will be available soon.
Effects of Airflow Disturbance on the Content of Biochemical Components and Mechanical Properties of Cucumber Seedling Stems
Abstract : In order to explore the changes in biochemical components and mechanical properties of cucumber seedlings with dwarfing characteristics under airflow disturbance treatment, ‘Jinyou No. 1’ cucumber seedlings were used as experimental materials and the split-plot design was used.
Asymmetric Total Synthesis of Hasubanan Alkaloids: Periglaucines A–C, N,O‐Dimethyloxostephine and Oxostephabenine
Abstract Asymmetric total synthesis of the hasubanan alkaloids periglaucines A–C, N,O-dimethyloxostephine and oxostephabenine is described. The key strategies include: 1) a RhI-catalyzed regio- and diastereoselective Hayashi-Miyaura reaction; 2) an intramolecular photoenolization/Diels–Alder (PEDA) reaction; and 3) bio-inspired intramolecular Michael addition and transannular acetalization.
Asymmetric Total Synthesis of Aglacins A, B, and E
Research Article Mengmeng Xu, Shanghai Key Laboratory of Green Chemistry and Chemical, Processes, School of Chemistry and Molecular Engineering, East China Normal University, China These authors contributed equally to this work. Search for more papers by this author Min Hou, Shanghai Key Laboratory of Green Chemistry and Chemical, Processes, School of Chemistry and Molecular Engineering, East China Normal University, China These authors contributed equally to this work.
Asymmetric Total Synthesis of Aglacins A, B and E
Research Article Shuanhu Gao Corresponding Author shgao@chem.ecnu.edu.cn East China Normal University, Department of Chemistry, 3663N Zhongshan Road, 200062 Shanghai, CHINA Search for more papers by this author PDF ShareShare Abstract An asymmetric photoenolization/Diels–Alder (PEDA) reaction, between electron‐rich 2‐methylbenzaldehydes and unsaturated γ‐lactones, was developed to directly construct the basic tricyclic core of aryltetralin lactone lignans.
Asymmetric Total Synthesis and Biosynthetic Implications of Perovskones, Hydrangenone, and Hydrangenone B
Perovskones and hydrangenones are a family of structurally complex triterpenoids that were mainly isolated from the genus Salvia medicinal plants. These isoprenoids exhibit a broad range of biological activities, such as antitumor and antiplasmodial activities. Here, we report the collective total synthesis of perovskone, perovskones C, D, F, hydrangenone, and hydrangenone B.
Sandwich-type surface-enhanced Raman scattering sensor using dual aptamers and gold nanoparticles for the detection of tumor extracellular vesicles
Sandwich-type surface-enhanced Raman scattering sensor using dual aptamers and gold nanoparticles for the detection of tumor extracellular vesicles You have access to this article Please wait while we load your content... Something went wrong. Try again?
Interleukin-4 enhances prostate-specific antigen expression by activation of the androgen receptor and Akt pathway
Comments Oncogene (2003) - doi: 10.1038/sj.onc.1206735 issn: 0950-9232 issn: 1476-5594 pubmed: 12970746 Soo Ok Lee, Wei Lou, Min Hou, Sergio A Onate, Allen C Gao
Subjective Visual Performance and Objective Optical Quality With Intraocular Lens Glistening and Surface Light Scattering
Hydrophobic acrylic intraocular lenses (IOLs) have become prevalent since the advent of small-incision cataract surgeries, possibly due to the reduced occurrence of posterior capsule opacification and calcification compared with IOLs made of other materials.1 However, glistenings and surface light scattering have been mainly reported in association with hydrophobic acrylic IOLs, specifically AcrySof IOLs (Alcon Laboratories, Inc., Fort Worth, TX).2 Glistenings are defined as sparkling bright...
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