Minerva G. Schafer

1. Introduction Click to copy section linkSection link copied! The synthetic virtuosity that chemists have acquired over almost two centuries to create myriad commercially useful chemicals and materials together with the triumphs of organic synthesis in delivering beguilingly complex natural products sum to one of the greatest technical achievements of our civilization.

3.6.1. Desaturase Activity of TAML Activators Activation of sp 3 C–H bonds by transition metal complexes continues to attract the attention of researchers (43−47) which arguably began in 1969 with publication of the pioneering study of Shilov and co-workers.

Abstract Bis-amido bis-sulfonamido version of TAML activators of peroxides [Fe{4-NO2C6H3-1,2-(NCOCMe2NSO2)2CHMe}(OH2)]− (1, TAML stands for tetraamidomacrocyclic ligand) catalyzes the oxidative bleaching of cyanidin 3-glucoside (cyanidin 3-O-β-glucopyranoside, Cy3G) by H2O2 so rapidly at neutral pH that the rate of disappearance of Cy3G does not depend on its concentration under all conditions studies. The rate law is free from the Cy3G term, viz. -d[Cy3G]/dt = kI[H2O2][1].