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Conditional Estimations for Seamless Phase II/III Clinical Trials Involving Multi-Stage Early Stopping
Conflicts of Interest The authors declare no conflicts of interest. Data Availability Statement Data sharing not applicable to this article as no datasets were generated or analyzed during the current study. Supporting Information Filename Description sim70693-sup-0001-FigureS1-S25-TableS1-S15.docxWord 2007 document , 3.9 MB Figure S1: The conditional bias and RMSE of the point estimators for the normal distribution under .
U-shaped association between HbA1c and all-cause mortality in CVD patients with diabetes - Scientific Reports
Abstract In this analysis, the association of baseline glycated hemoglobin (HbA1c) levels with all-cause mortality in cardiovascular disease (CVD) patients with diabetes was investigated using data from NHANES 1999–2014. Under examination were 845 CVD patients who had diabetes and were followed for a median follow-up of 7.3 years, and an all-cause mortality rate of 22.60% was observed.
High‐speed centrifugation rather than Lipoclear reagent can be used for removing the interference of lipemia on serological tests of infectious diseases: AIDS, hepatitis B, hepatitis C, and syphilis by chemiluminescent microparticle immunoassay
CONFLICT OF INTEREST STATEMENT The authors declare no conflict of interest. REFERENCES 1, , . Interferences in immunoassays: review and practical algorithm. Clin Chem Lab Med. 2022; 60(6): 808-820. 2, , , , . Optimization of hemolysis, icterus and lipemia interference thresholds for 35 clinical chemistry assays. Pract Lab Med. 2021; 25:e00232. 3, , . Effects of marked hypertriglyceridemia and lipid clearance techniques on canine biochemistry testing. J Vet Diagn Invest. 2019; 31(4): 546-553. 4, .
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