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Mingwu Chen

As seen in: Nature, Wiley Online Library, Frontiers, JAMA Network, Dove Medical Press
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Articles by Mingwu Chen

Prevalence of Diagnosed Type 2 Diabetes Among US Children and Adolescents

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By Xiaodong Zang, Meiyuan Chen, Yang Du, Buyun Liu, Mingwu Chen, Guifeng Xu, Wei Bao
| JAMA Network Verified
Type 2 diabetes (T2D) in children and adolescents has become an escalating global public health challenge.1,2 In the US, previous studies have reported T2D prevalence among youths based on surveillance in multiple regions3,4; however, nationally representative estimates remain lacking.2 To fill this gap, we analyzed data from a nationally representative survey to estimate prevalence of diagnosed T2D among US children and adolescents.
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Proinflammatory monocyte-derived granulocyte-macrophage colony-stimulating factor fuels airway inflammation in bronchopulmonary dysplasia

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By Shushu Wang, Xuesong Wang, Dongyao Wang, Binqing Fu, Mingwu Chen, Yong Lv, Huiru Wang, Yonggang Zhou, Haiming Wei, Haoquan Zhou
| Nature Verified
Abstract Bronchopulmonary dysplasia (BPD) remains a leading cause of morbidity and long-term respiratory complications in preterm neonates. Effective strategies for moderate-severe BPD are currently lacking. Tracheal aspirate (TA) samples were collected from 62 preterm neonates, and the immune cell composition was analyzed using multicolor flow cytometry. Subsequently, CD14+ monocytes were isolated and purified from the TA samples for transcriptomic sequencing analysis.
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Agreement and diagnostic performance of a smartphone-based bilirubin assessment tool for screening neonatal hyperbilirubinemia

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By Ya Ting Zhao, Tonghui Suo, Fengqin Zhang, Mingwu Chen, Anlan Xu
| Frontiers
Abstract Background: Neonatal hyperbilirubinemia is common and may lead to severe neurological injury if not detected and treated promptly. Total serum bilirubin (TSB) remains the reference standard, while transcutaneous bilirubin (TcB) is commonly used for non-invasive screening. Smartphone-based bilirubin assessment may provide a supplementary approach for neonatal jaundice screening.
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Ginkgolide B Alleviates Airway Inflammation in Hyperoxia Lung Injury

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By Xuesong Wang, Mingwu Chen, Yong Lv
| Wiley Online Library Verified
BALF bronchoalveolar lavage fluid BPD bronchopulmonary dysplasia GB Ginkgolide B GM-CSF granulocyte-macrophage colony-stimulating factor GRO growth-related oncogene IL interleukin KC CXCL1 LCN2 lipocalin 2 MMP12 matrix metallopeptidase 12 MPO myeloperoxidase NICHD National Institute of Child Health and Human Development NO nitric oxide PAF platelet activation factor PGE2 prostaglandin E2 1 Introduction Bronchopulmonary dysplasia (BPD) is a severe respiratory complication in premature infants,...
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Advanced LUAD therapy with EGFR mutation and BRAF V600E

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By Xiang L. Tan, Zuotao Wu, Mingwu Chen
| Dove Medical Press
Back to Journals » OncoTargets and Therapy » Volume 17 Authors Tan X, Wu Z, Chen M Received 14 December 2023 Accepted for publication 20 March 2024 Published 9 April 2024 Volume 2024:17 Pages 307—312 DOI https://doi.org/10.2147/OTT.S454902 Checked for plagiarism Yes Review by Single anonymous peer review Peer reviewer comments 2 Editor who approved publication: Dr Nagashree Seetharamu Xiang Tan,* Zuotao Wu,* Mingwu Chen Department of Thoracic Surgery, The First Affiliated Hospital of...
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