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Minle Tian

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Articles

The choroid plexus, cognitive decline, and incident dementia: insights from the UK Biobank

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By Tianyu Yu, Xiaolei Han, Xin Huang, Hongli Chang, Xinyu Liu, Xiaomeng Li, Yiming Guo, Jiahao Ding, Xuewei Li, Yi Dong, Yifeng Du, Lin Lu, Chengxuan Qiu, Yongxiang Wang, Minle Tian, Ming Mao
| Nature Verified
Abstract The choroid plexus (CP) plays a crucial role in cerebrospinal fluid secretion and the maintenance of brain homeostasis. Its structure and function have been implicated in the pathogenesis of dementia; however, the longitudinal associations of CP with dementia and structural brain biomarkers remain unclear. This prospective cohort study utilized data from the UK Biobank, including 45,306 participants (mean age, 64 years; 47.2% men) who underwent 3.0 T multiparametric brain MRI scans.
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