Miriam von Stern on Muck Rack

Miriam von Stern

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Articles

ATF6 activation alters colonic lipid metabolism causing tumor-associated microbial adaptation

|
By Olivia Coleman, Adam Sorbie, Alessandra Riva, Miriam von Stern
| biorxiv.org
Abstract Endoplasmic reticulum unfolded protein responses (UPRER) contribute to cancer development and the activating transcription factor 6 (ATF6) is involved in microbiota-dependent tumorigenesis. Here, we substantiate the clinical relevance of ATF6 in early-onset and late colorectal cancer patient cohorts.
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