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Mirko Baruscotti on Muck Rack

Mirko Baruscotti

As seen in: Nature, The European Heart Journal
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Articles

Hcn4-deficient zebrafish embryos develop a normal left‒right axis

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By Alberto Diana, Andrea Masseroni, Adèle Faucherre, Chris Jopling, Elena Menegola, Francesca Di Renzo, Renato Bacchetta, Annalisa Bucchi, Mirko Baruscotti, Patrizia Benzoni, Marcella Rocchetti, Andrea Barbuti, Luca Del Giacco, Martina Arici
| Nature Verified
Abstract Background Left‒right (LR) asymmetry is a well-conserved feature of the Vertebrate body plan and is essential for the correct positioning and morphogenesis of visceral organs.
Open in Who Shared Issue with article?

A gain-of-function mutation in the cardiac pacemaker HCN4 channel increasing cAMP sensitivity is associated with familial Inappropriate Sinus Tachycardia | European Heart Journal

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By Mirko Baruscotti, Annalisa Bucchi, Raffaella Milanesi, Manuel Paina
| The European Heart Journal Verified
AbstractAims Inappropriate Sinus Tachycardia (IST), a syndrome characterized by abnormally fast sinus rates and multisystem symptoms, is still poorly understood. Because of the relevance of HCN4 channels to pacemaker activity, we used a candidate-gene approach and screened IST patients for the presence of disease-causing HCN4 mutations.Methods and results Forty-eight IST patients, four of whom of known familial history, were enrolled in the study.
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