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Mirna Barsoum on Muck Rack

Mirna Barsoum

As seen in: Nature, Frontiers
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Articles

Functional integration of LCIB, a component of the algal carbon-concentrating mechanism, enhances carbon assimilation, nitrogen-use efficiency, and biomass in tobacco

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By Mirna Barsoum, Matthias Buntru, Stefan Schillberg
| Frontiers
Abstract Engineering carbon-concentrating mechanisms (CCMs) into C3 crops is a promising strategy to improve photosynthetic efficiency by increasing the availability of CO2 near the active site of ribulose-1,5-bisphosphate carboxylase/oxygenase (RuBisCO), the enzyme responsible for carbon fixation. The biophysical CCM of the green alga Chlamydomonas reinhardtii includes stromal limiting CO2-inducible protein B (LCIB) protein, which contributes to inorganic carbon retention.
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Sequential deregulation of histone marks, chromatin accessibility and gene expression in response to PROTAC-induced degradation of ASH2L - Scientific Reports

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By Mirna Barsoum, Roksaneh Sayadi-Boroujeni, Alexander Stenzel, Juliane Luscher-Firzlaff
| Nature Verified
Abstract The trithorax protein ASH2L is essential for organismal and tissue development. As a subunit of COMPASS/KMT2 complexes, ASH2L is necessary for methylation of histone H3 lysine 4 (H3K4). Mono- and tri-methylation at this site mark active enhancers and promoters, respectively, although the functional relevance of H3K4 methylation is only partially understood. ASH2L has a long half-life, which results in a slow decrease upon knockout. This has made it difficult to define direct consequences.
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The Parauncinula polyspora Draft Genome Provides Insights into Patterns of Gene Erosion and Genome Expansion in Powdery Mildew Fungi

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By RWTH Aachen, Hungarian Academy, Lamprinos Frantzeskakis, Mirna Barsoum
| asm.org
Research Article | Host-Microbe Biology Lamprinos Frantzeskakis, Márk Z. Németh, Mirna Barsoum, Stefan Kusch, Levente Kiss, Susumu Takamatsu, Ralph Panstruga B. Gillian Turgeon, Editor DOI: 10.1128/mBio.01692-19 ABSTRACT Due to their comparatively small genome size and short generation time, fungi are exquisite model systems to study eukaryotic genome evolution.
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