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Mishana Truitt on Muck Rack

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Articles

Penta-EF-Hand Protein Peflin Is a Negative Regulator of ER-To-Golgi Transport

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By John Sargeant, Mariah Rayl, Mishana Truitt, Aaron Held, Kevin Thorsen
| PLOS
Luminal calcium regulates vesicle transport early in the secretory pathway. In ER-to-Golgi transport, depletion of luminal calcium leads to significantly reduced transport and a buildup of budding and newly budded COPII vesicles and vesicle proteins. Effects of luminal calcium on transport may be mediated by cytoplasmic calcium sensors near ER exits sites (ERES).
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