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Mithusha Peragerasingam on Muck Rack

Mithusha Peragerasingam

As seen in: BioRxiv
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Articles

ROMO1 and Mitochondrial Complex II/SDH are Required for Spare Respiratory Capacity and Glucose Homeostasis in Mice

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By Lisa Wells, Qian Yang, Caterina Iorio, Mithusha Peragerasingam
| BioRxiv
Abstract Aims/Hypothesis: Reactive oxygen species modulator 1 (ROMO1) is a highly conserved inner mitochondrial membrane protein that senses reactive oxygen species and regulates mitochondrial dynamics. ROMO1 is required for mitochondrial fusion in vitro, and silencing ROMO1 increases sensitivity to cell death stimuli. The physiological role of ROMO1 remains unclear.
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